Abstract: The drag reduction of super-hydrophobic surface is studied with theoretical computation and numerical simulation methods based on slip theory. The difference between theoretical computation and numerical simulation for laminar flow was minor, and the drag reduction proved to be approximately equal to the ratio of slip velocity to bulk velocity. Considering the realized slip velocity range, the numerical simulation results for turbulent flow show that the drag coefficient of underwater vehicle model was not obviously influenced by the super-hydrophobic surface in turbulent flow.