Abstract: In this paper, methoxy poly(ethylene glycol)-block-poly(lactic-co-glycolic acid) (mPEG-b-PLGA) micelles and poly(acrylic acid) (PAA) layers were alternately deposited on the silicon substrate, linked by hydrogen bonds. The structure of the micelles films were characterized by contact angle measurements, ellipsometric thickness measurements and X-ray photoelectronic spectroscopy, atomic force microscopy. Anti-wear properties of the films were also evaluated on a ball-on-plate tribometer. It was found that the mPEG-b-of PLGA micelle films were uniformly deposited and offered excellent lubrication. There is a possibility of such thin films as anti-inflaming and lubricating coating used on catheter or device implanted in vivo.