Abstract: By using a UMT-II tribometer, the effects of scrub facial cleanser with different size, amount and hardness scrub particles on the tribological properties of human skin have been investigated under the simulated face washing conditions. The results show that the aged corneous layers on the skin surface have been removed by the scrub facial cleanser under reciprocating sliding wear mode, which result in decrease in the skin surface roughness and increase in skin conductance, skin hydration, adhesion and friction coefficient. Seeing that the scrub facial cleanser B with two kinds of size and moderate volume and hardness scrub particles remove more aged corneous layer, the skin permeation to the moisturizing cosmetic is better than those removed by the other two scrub facial cleansers. Due to gender differences in skin surface structure, the effect of scrub facial cleanser on the skin surface of males is more significant than that of females.